Adding too much liquid reduces the final concentration, while adding too little increases it
Food and Drug Administration (FDA) DailyMed Label: Bacteriostatic Water for Injection (Provides official labeling, storage instructions, and preservative information) United States Pharmacopeia (USP) USPNF General Chapters & Monographs (Defines standards for sterile water for injection and pharmaceutical quality requirements) World Health Organization (WHO) WHO Good Storage and Distribution Practices (Guidelines for temperature control, sterility, and pharmaceutical handling) American Society of Health-System Pharmacists (ASHP) (Clinical guidance on sterile product handling and multi-dose vial use) FDA Guidance on Sterile Drug Products (Aseptic handling, contamination risk, and storage principles)
Cagrilintide has a half-life of approximately 7-8 days, supporting once-weekly research protocols
Both contain the same 15-amino-acid peptide core
For example, other drug makers might pursue this approach going forward, compared to the more rigorous FDA approval pathway