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Lactate further augments neutrophil functions, including chemotaxis, phagocytosis, oxidative burst and neutrophil extracellular trap formation, via energy provision and PI3K/Akt signaling, which may exacerbate tissue cell ferroptosis (105)

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Environ Int 112:287293

Growth hormone stimulates the tyrosine phosphorylation of the insulin receptor substrate-1 and its association with phosphatidylinositol 3-kinase in primary adipocytes