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338 A single strip of medical silicone tape, placed vertically under the nose and across both lips, was used to seal the mouth closed in the study

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Indeed metformin inhibits the mitochondrial oxidative phosphorylation complex I, leading to increased cellular AMP levels and subsequent stimulation of AMPK, an enzyme that plays key roles in the regulation of cellular energy homeostatis

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10.1016/j.cell.2016.12.039 286 VettoreL.WestbrookR

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