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In a human clinical trial, a marked increase in cellular glutathione levels was seen regardless of its initial (basal) concentration
Thus, carnitine deficiency may cause intracellular accumulation of fatty acids, with a subsequent deficiency of energy substrates (such as acetyl-CoA metabolites)
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Conversely, patients with long-standing obesity, multiple previous weight loss attempts, or significant metabolic dysfunction may benefit from indefinite therapy
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