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It behaves like a little hormone factory, churning out its own inflammatory estrogen (estrone) and driving up insulin, both of which feed cancers like breast and endometrial
The issue is even more egregious given that the concentration of a urine sample is always measured by the testing laboratory, and the adjustment calculation is very simple
It is a reasonable precaution, not a strict requirement
This ensures you get the best results
[1] Importance of Titration Gradual dose escalation is critical to balancing efficacy and tolerability
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