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Furthermore, both adults and eggs of Schistosoma mansoni can induce M2-type polarization of M by peroxisome proliferator-activated receptor (PPAR) activation, which is beneficial to parasite survival ( Figure 4 )

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Parkinson protein 2-dependent pathway PTEN-induced putative kinase 1 (PINK1/PARK6) and Parkin (PARK2), initially identified as key proteins associated with Parkinsons disease, have been recognized for their pivotal roles in mitophagy [24]

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