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Orlistat is available both on prescription (120 mg) and over-the-counter in lower doses (60 mg as Alli)
This criterion ensured consistent capture of baseline BMI, comorbidity, and prescription data from the start of each patients record and reduced misclassification of prior GLP-1 RA exposure
Tirzepatide engages the GLP-1 receptor and, as a dual agonist, the GIP receptor slowing gastric emptying, blunting post-meal glucose, reducing appetite, and increasing satiety
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