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5-Amino-1MQ (5-amino-1-methylquinolinium) is a selective inhibitor of NNMT nicotinamide N-methyltransferase

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Heneka et al., 2025) without any contribution from bone-marrow-derived monocytes to the microglial pool, at least under homeostatic conditions (Masuda et al., 2020), and healthy brain parenchyma has little macrophage and monocyte infiltration due to blood-brain barrier (BBB)

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