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The addition of exosomes to hydrogels has shown an excellent effect on the healing of diabetic wounds, a reduction in the formation of scar tissue, and promotion of the production of skin appendages, with a positive effect on skin regeneration (Wang et al., 2019a)

Genetic and epigenetic factors determining MASLD have been recently reviewed by Jonas and Schurmann (Jonas and Schurmann 2021), and the role of gut microbiota in mediating MASLD development was summarized by Campo et al