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Oral absorption is considered too undependable to rely on in patients with pernicious anemia or other conditions resulting in malabsorption of vitamin B12

Injecting into or near blood vessels accidentally can lead to rapid systemic absorption

USP specification calls for Type I borosilicate glass, pharmaceutical-grade rubber stoppers, and machine-applied aluminum crimps

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For someone with mild fatigue and slightly low blood levels, a conservative approach of one injection every four weeks might be sufficient