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GLP-1-induced AMPK and LXR-mediated ABCA1 expression are involved in GLP-1 protective effects (Figure 8)
Aronne LJ et al., SURMOUNT-5 head-to-head, NEJM 2024 (NEJMoa2416394) : tirzepatide vs semaglutide, advantage tirzepatide of approximately 6 points
Kidney Protection Chronic kidney disease (CKD) is a common complication of Type 2 diabetes, affecting nearly one in three people with the condition
Its primarily approved for chronic weight management in adults with obesity or who are overweight and have at least one weight-related condition, like diabetes, high blood pressure or a risk of cardiovascular events
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