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Although there are many ongoing large CVD outcome trials of GLP-1 RA treatment (Table 1), more simultaneous investigation of the causal relationship between GLP-1 RA administration and useful surrogate measures of CVD, including carotid IMT, would help us understand the potential mechanisms through which GLP-1 RAs may result in favorable cardiovascular outcomes in patients with T2D
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By targeting these fibres directly, Pure Impact helps maintain functional muscle, supporting metabolism, posture, and the structural integrity of the body during weight loss
The fourth strategy consists of characterising the genetic determinants of high human radioresistance in conjunction with clinical translation via multiplex genetic engineering
The relative contributions of the direct effects of incretin receptor agonists on fibrosis versus the secondary effects of weight loss and systemic reductions in inflammation remain to be delineated
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