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Among those who have used GLP-1 drugs, about half report they have experienced nausea and about one-third experienced diarrhea
In addition, PCOS is commonly associated with metabolic disorders, such as obesity, insulin resistance, type-2 diabetes (T2D), dyslipidemia, and cardiovascular dysfunction 5,6
Unlike weight loss medications developed specifically for metabolic disease, semaglutide's interaction with enteric neurons and intestinal smooth muscle suggests a direct relationship with IBS symptomsthough clinical outcomes vary significantly between individuals
Cleveland Clinic explains that muscle is metabolically active, meaning it requires energy to maintain itself and burns calories even at rest. Harvard Health Publishing also notes that Muscle burns more calories than fat
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