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Description

The structurally simplified Ang IV peptidemimetic 16 was almost as active as Ang IV as an IRAP inhibitor while 17 was five-fold and 18 and the open chain 19 were 20-fold less active (Figure 5)

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Any human application would need to be medically supervised and conducted under appropriate oversight

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The Pro-Gly-Pro C-terminal extension provides partial protection against proteolysis but does not prevent systemic clearance

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328.41 g/mol Purity 98% CAS No

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Both peptides are administered through subcutaneous injection once per week

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