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D + I 20212023, by the European Commission through the Horizon 2020 European Training Networks program, grant number H2020-MSCA-ITN-308 2016 721532 and by the Madrid Region Government Network Program in Biosciences, grant number S2022/BMD-7434 (ASAP-CM)

While some metabolic adaptation still occurs, the direct appetite suppression provided by the medication means that the ghrelin increase is less impactful

These subsequent injuries involve the disturbance of the blood-brain barrier (BBB), excitotoxicity induced by glutamate, oxidative stress, and neuroinflammation, all of which can develop in a time-dependent manner following the initial mechanical injury (Chiu et al., 2016)

10.1016/j.jep.2012.09.048 161 WangX.MaJ.ZhangS.LiZ.HongZ.JiangL.et al (2021)