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The high expression of drug efflux pump multidrug resistance 1 (MDR1) gene, and the MDR1-encoded P-glycoprotein (P-gp), an ATP-binding cassette transporter, are significantly implicated in the development of multidrug resistance (MDR) [32]
Glutathione exists in two forms: reduced (GSH) and oxidized (GSSG)
Koshikawa N, Maejima C, Miyazaki K, Nakagawara A, Takenaga K
M.GonzalezGonzalezJ.GarciaCamareroT.ConsuegraSanchezL.et al (2017)
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