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The safety profile was consistent with GLP-1 receptor agonists, primarily featuring transient, mild-to-moderate gastrointestinal adverse events (e.g., nausea, 55%), with low discontinuation rates (6-8.4%)
Metabolic Dissociation: studies measure adipose endpoints while holding IGF-1 and glucose parameters unchanged
nitric oxide promotes the relaxation of arterial walls, leading to vasodilation
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