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Elevated cortisol has been shown to impair tendon healing at the cellular level in animal models
Furthermore, combination therapy trials exploring the synergistic effects of GLP-1RAs with biologics could uncover new approaches for treatment, enhancing the management both metabolic and immunologic aspects in PsA
Although proven effective, GLP-1 RAs have been associated with numerous GI adverse events
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Consistent with what we reported while studying endothelial cells [30], we found that ALCAR downregulates in PCa cells the release of pro-angiogenic factors involved in inflammation and endothelial recruitment and activation such as VEGF, CXCL8, CCL2 and CXCL12
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