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Overall, tirzepatide reduced the AHI, body weight, hypoxic burden, high-sensitivity C-reactive protein concentration, and systolic blood pressure, and it improved sleep-related patient-reported outcomes

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Researchers should have protocols in place for managing adverse events and should document all adverse effects for safety tracking

Laboratory research has examined its interaction with nitric oxide (NO) pathways, growth factor modulation including VEGF and EGF, and the FAK-paxillin signaling cascade used in tissue remodeling studies