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To determine whether reduced Kcnq5 expression in excitatory neurons of the mPFC is sufficient to induce autism-like phenotypes, we used an AAV-mediated approach to selectively knock down Kcnq5 in excitatory neurons of mPFC in wild-type mice (Fig
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
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4 Discussion Based on current RCT evidence, our meta-analysis showed that semaglutide significantly reduces MACE risk in patients with T2DM, primarily by lowering nonfatal myocardial infarction risk, with no significant effects on cardiovascular death or nonfatal stroke
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