Mechanism-specific assays should then assess mitochondrial respiration, antioxidant capacity, EV particle and cargo profiles, immunomodulatory suppression, angiogenic potency, or barrier protection
CABI, 2008 Taxonomic history and synonym information on these pages is drawn from many sources but in particular from the British Mycological Society's GB Checklist of Fungi
In contrast, the detrimental effect of mitophagy mostly occurs in scenarios of excessive activation or abnormal regulation: when cells encounter sustained and severe pathological stress (such as severe ischemia and severe inflammation), mitophagy is abnormally activated, which excessively degrades functionally normal mitochondria, leading to disorders of cellular energy metabolism, insufficient ATP synthesis, and simultaneous disruption of the normal proliferation and renewal balance of mitochondria in cells
10.1006/bbrc.1996.1121 190 LucottiP.MontiL.SetolaE.La CannaG.CastiglioniA.RossodivitaA.et al (2009)
Presented for research literature review only Kutlik MT et al