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In addition, spironolactone acts as an androgen receptor blocker by competitively inhibiting dihydrotestosterone at its receptor sites, and at high doses, spironolactone interferes with steroid synthesis in the adrenal glands and gonads
PMID 28365374
Chronic xerostomia significantly increases the risk of dental disease, and early intervention can prevent serious complications
doi: 10.3389/fnagi.2019.00311 189 XuFArmstrongRUrregoDQazzazMPeharMArmstrongJNet al
Avoid using this product on open wounds or damaged skin
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