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Aside from the unknown temporal dynamics of mitochondrial dysfunction, clinical trials in neurodegenerative diseases, in general, face unique challenges with long interventional periods, the need for sophisticated trial designs (delayed-clinical trials or adaptive designs), and a priori patient-stratification

While 1544% of patients experience gastrointestinal symptoms like nausea, these typically represent expected pharmacologic effects rather than true gastroparesis, which requires objective confirmation through gastric emptying studies

Gastric emptying scintigraphy (GES) is the current gold standard

There are eggs , cottage cheese, shredded cheese, and black beans all contributing to the protein content

For those with predictable basic weekly exercise (or no exercise), its far easier to go the beginner route