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Most people start with a loading phase, typically one injection per week for 4 to 6 weeks

Vitamin B12 shots may not be suitable for people with a history of: sensitivity to vitamin B12 Lebers disease, which affects the optic nerve kidney problems hypokalemia (low potassium levels) deficiencies in other nutrients, particularly folic acid and iron Vitamin B12 injections typically begin to work straight away

In one study, mice treated with 20mg/kg of 5-amino-1mq three times daily for 11 days experienced a 5.1% reduction in body weight from baseline

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