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Note the constraint: four weekly doses from a 10 mg vial takes four weeks, which sits at the outer edge of the 24 week refrigerated in-use window for reconstituted solution
The key insight is the third pathway
Tirzepatide and retatrutide (single molecule): A single engineered molecule that hits multiple receptors simplifies the formulation to one compound with one pharmacokinetic profile, and allows the balance of receptor activation to be tuned at the molecular-design level
181 , R211R234 (2019)
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