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When GLP-1 is secreted from L-cells through the TGR5 agonist, it stimulates GLP-1R in enterochromaffin cells and induces serotonin or 5-hydroxytryptamine (5-HT) secretion from these cells
Many women benefit from focusing on protein, fibre, hydration and realistic meal structure rather than extreme dieting
Digestive Diseases and Sciences, 52 (9), 2387-2395
Despite these beneficial metabolic effects, native GLP-1 has significant pharmacokinetic limitations that restrict its therapeutic utility
Early Weight Changes: Some individuals may see a few pounds come off, while others might see more substantial changes
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