Last month (May 2025), Novo Nordisk and Septerna, a San Francisco, California-based bio/pharmaceutical company focused on GCPRs, formed an exclusive global collaboration and license agreement to discover, develop, and commercialize oral small-molecule medicines for treating obesity, Type 2 diabetes, and other cardiometabolic diseases, in a deal worth up to $2.2 billion ($200 million upfront and near-term funding and $2 billion in milestone payments)
A significant proportion (up to 70 %) discontinue GLP-1 treatment within one year
Acquisition, analysis, or interpretation of data: H.S.K., T.Y., C.H.J., J.Y.P., W.J.L
Glutathione is the most abundant antioxidant
and (2) the presence of concomitant medications that may have been prescribed for the treatment of epileptic disorders, such as VPA