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10.1016/0378-8741(89)90009-3 29 BettigoleS

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Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg and gradually titrated upward (5 mg, 7.5 mg, 10 mg, 12.5 mg, to a maximum of 15 mg) based on therapeutic response and tolerability

The development reflects the rapidly expanding market for GLP-1based obesity treatments, which are transforming how metabolic diseases such as obesity and diabetes are managed

-factor One of two peptide hormones in Saccharomyces cerevisiae that are responsible for synchronized mating between yeast cells of opposite mating type