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At the sample session on the experimental day, the animals were placed in the open arena, which had two identical objects aligned with a random wall of the arena, at a distance of 10 cm, and they were allowed to freely explore for 5 min (Figure 2B)

The same authors conducted another systematic review of 78 randomized clinical trials on antioxidant supplements including beta-carotene, vitamin A, vitamin C, vitamin E, and selenium (alone or in combination)

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Even though patients with RA showed higher plasma levels of superoxide dismutase (another of the bodys super antioxidants), they also had high levels of pro-oxidants, and increased nitric oxide, an inflammatory marker