Since the fact that SS has anti-proliferative and anti-angiogenic effects and given that its half-life is very short (13 min), as well as the wide spectrum of its biological responses, led to the need to develop selective stable receptor agonists that are bind strongly to selective SS receptor subtypes, therefore, in addition to blocking GH secretion (e.g., treatment of Acromegaly), these SS agonists are being used for the therapy of neuroendocrine tumors, diabetic complications (nephropathy, retinopathy), anti-neoplastic therapies
For hair specifically, the relevant subset of these pathways translates into improved follicle environment, reduced oxidative damage to dermal papilla cells, and a calmer inflammatory state three of the four root causes of androgenetic alopecia, addressed simultaneously by a single molecule
Mounjaro also comes as a pen injector to make it easy for the patient to administer
More serious side effects, some potentially requiring hospitalization, can also occur, such as: Pancreatitis a painful inflammation of the pancreas
Combination approaches using local injection for one peptide and systemic for the other represent another valid strategy