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Review of T-2307, an investigational agent that causes collapse of fungal mitochondrial membrane potential
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About this article Cite this article Skonberg, C., Olsen, J
Jing et al
118 In ER/HER2 breast cancer, hyperactivated AKT1 binds to the kinase domain of TBK1, disrupting the STING-TBK1-IRF3 complex, thereby impairing downstream interferon signaling and blocking innate immune responses triggered by DNA damage
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