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1060 Characterizing Variability in Patient Global Impression of Change (PGIC) and Severity (PGIS) Measures: Towards Standardization of PRO Design to Improve Development, Comparability, Translatability, and the Patient Experience Tim Poepsel 1 , Rebecca Israel 2 , Allyson Nolde 3 , Rachael Browning 4 , Chryso Hadjidemtriou 5 1 RWS, St

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Similarly, another study found that NAC supplementation increased GSH-Px4 protein levels in the placenta, inhibiting placental ferroptosis, which was associated with reduced pregnancy loss in PCOS model mice [58]

The within-group Cohens d effect size for improvement (difference between the mean of screening, first and second baseline, and posttreatment) was large ( d = 1.46