The study found that people who stopped taking tirzepatide after 36 weeks regained much of their lost weight within a year, while those who continued to take it lost even more, about 25% of their original weight on average

These include: Severe headaches , particularly if sudden-onset or different from usual patterns Visual disturbances such as blurred vision or seeing spots Chest pain or pressure , which may indicate cardiovascular complications (call 911) Shortness of breath or difficulty breathing, especially with exertion (call 911 if severe) Neurological symptoms including facial drooping, arm weakness, speech difficulties (call 911) Severe dizziness or lightheadedness , particularly upon standing (suggesting hypotension) Nosebleeds that are difficult to control Confusion or difficulty concentrating Patients should also promptly report semaglutide-specific concerns that may require immediate evaluation: Severe, persistent abdominal pain (possible pancreatitis) Right upper quadrant pain, fever, or yellowing of skin/eyes (possible gallbladder disease) Signs of allergic reaction including rash, swelling, or difficulty breathing New or worsening vision problems (potential diabetic retinopathy complications) Persistent nausea, vomiting, or diarrhea can lead to dehydration, electrolyte imbalances, and secondary blood pressure changes

The results were impressive: GLP-1 medication c ounteracted age-related decline across multiple body systems , including the circulatory system and tissues throughout the body [10]
transition to 12 injections per week for maintenance dosing to sustain pigmentation [3]
How much you regain depends on a number of factors: How much weight you lost initially How long you were on treatment What lifestyle changes youve made and maintained People who have genuinely changed their eating habits and activity levels are far more likely to keep the weight off after Wegovy than those who relied solely on the medication