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effects stop when drug stops
An unbiased genome-wide siRNA screen for suppressors of ferroptosis found that loss of cysteinyl-tRNA synthetase (CARS) increases cystathionine and activates the transsulfuration pathway to suppress ferroptosis, which is induced by the well-known system ( SLC7A11 ) inhibitor, erastin (Table 1) (Hayano et al., 2016)
While your body can produce antioxidants naturally, they are ideally supplied by foods and supplements like N-acetyl-L-cysteine (NAC)
10.1016/j.ecoenv.2022.113785 Ecotoxicol
Ethics declarations Competing interests Diagnostic assay for methylation in the GSTP1 gene
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