Pratipanawatr T, Pratipanawatr W, Rosen C, Berria R, Bajaj M, Cusi K, Mandarino L, Kashyap S, Belfort R, DeFronzo RA
The membrane was incubated at 4C overnight with a primary antibody: anti-IB- (1:1500), anti-NF-B p-65 (1:1000), anti-MMP-9 (1:1000), anti-albumin (1:5000), anti-occludin (1:1500), anti-claudin-5 (1:1000) (Abcam, Cambridge, MA, United States), anti-p-AMPK (1:1000), anti-AMPK (1:1000), anti-p-NF-B p-65 (1:1000) (Cell signaling, Boston, MA, United States), anti-GLP-1R (1:200), and anti--actin (1:5000) (Santa Cruz Biotechnology Inc.)
The oxidation status of Mic19 regulates MICOS assembly
(2020, June 22)
169 First-generation agents, including verapamil and cyclosporin A, showed in vitro efficacy but were hampered by off-target toxicity and limited clinical applicability