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Funnel plots showed a symmetrical distribution of most SNPs around the central estimate, indicating the absence of significant directional pleiotropy or bias (Supplementary Figure S3)

Chronic calorie restriction often leads to metabolic damage, decreased free T3 levels, and increased leptin levels, resulting in weight gain over time

Carnitine and microbiota Carnitine molecules that are not absorbed can either be excreted or be metabolized by intestinal microbiota (Ghonimy et al

First described by Novo Nordisk researchers, ipamorelin is notable for its selectivity in stimulating growth hormone release without significantly affecting other pituitary hormones such as ACTH, prolactin, FSH, LH, or TSH in preclinical models

DHA is key to the proper function of cell membranes