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& Lit, L
Rosen LS, Brown J, Laxa B, Boylos L, Reiswig L, Henner WD, Lum RT, Schow SR, Maack CA, Keck JG, Mascavage JC, Dombroski JA, Gomez RF, and Brown GL
[12] These findings do not establish efficacy for muscle growth, fat loss, anti-aging, sleep improvement, bone-density treatment, or any other personal-use application
C677T: G/G: typical function A/G: enzyme function decreased by ~40% A/A: enzyme function decreased by 7080% A1298C: T/T: typical function G/T: slightly decreased function G/G: enzyme function decreased by ~20% Are there other MTHFR variants that matter
Its copper-mediated influence on lysyl oxidase activity, an enzyme critical to collagen cross-linking, is one proposed mechanism underlying these observations
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