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a true vitamin B12 overdose is extremely rare

Its a desperate scramble that brings us to articles like this, where we want some reassurance about a new silver bullet

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By 1971, John Brown, who trained in the laboratory of Victor Mutt in Stockholm, had isolated a candidate hormone from porcine intestine, a peptide of 42 amino acids, which was first named as gastric inhibitory polypeptide (GIP) [6]