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Semaglutide: Targets only GLP-1 receptors
How It Works for Weight Loss Phentermine affects the central nervous system, stimulating the release of neurotransmitters like norepinephrine to reduce hunger
Studies show it can lead to more weight loss than semaglutide in patients with type 2 diabetes
However, while direct CSF measurements confirm limited but measurable BBB penetration, the clinical translation of its effects remains a key challenge
This objective data provides an early warning system and allows for protocol adjustments long before any issue becomes clinically significant
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