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How does topiramate (Topamax) help with weight loss

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Clinical evidence demonstrates that GLP-1 medications continue to provide metabolic benefits, including improved glycaemic control and, in people with type 2 diabetes, cardiovascular risk reduction, even when weight loss stabilises

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This class of drugs improves pancreatic islet dysfunction, however are restricted the studies that verified these same effects in T1DM model, whether in the presence or absence of detectable beta cell function 47

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(19,20) Some newer experimental approaches that may have promise are magnetic or electrical stimulation of the brain examples of which include transcranial magnetic stimulation (TMS) and deep brain stimulation and vagus nerve stimulation using an implanted device

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