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Interestingly, in a 21% O 2 atmosphere the cytotoxic effect of Ru(II)-OH, NP2, and NP4 was found to be in the same range (IC 50 = 6.110.4 M)
[16] [17] Funcin [editar] En el estado reducido, el grupo tiol de la cistena es capaz de donar un equivalente de reduccin (H + + e - ) a otras molculas inestables, tales como las especies reactivas de oxgeno
Some studies suggest that NSAIDs can interfere with mitochondrial function, leading to an increase in reactive oxygen species (ROS)unstable molecules that contribute to oxidative stress
That means the same dose has less room to spread out and dilute in a woman of similar age and weight, so its effects are likely to be stronger
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