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In individuals with type 2 diabetes mellitus, the incretin effect is diminished, with impaired beta-cell responsiveness to GIP being a dominant defect, while GLP-1 secretion may be modestly reduced in some patients

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social media data from the media monitoring tool Talkwalker, Danone found that out of a 50% spike in searches related to weight loss medications during Super Bowl LIX (versus pre-game hours), 21% of the overall GLP-1 discussion focused on nutrition-related conversations