does semaglutide only work by reducing appetite Most weight loss medications through a single hormone pathway. Tirzepatide works through two. targets GLP-1, a hormone involved in slowing digestion, increasing fullness, and hunger signals. Tirzepatide activates both Diet on semaglutide: complete guide

Diabetologia 67(Suppl 1):abstract 81 Ali A, Khan D, Dubey V, Tarasov AI, Flatt PR, Irwin N (2024) Comparative effects of GLP-1 and GLP-2 on beta-cell function, glucose homeostasis and appetite regulation

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The post lists a type 2 diabetes diagnosis with inadequate control on other medications, or a BMI at or above 27 combined with weight-related comorbidities such as hypertension, sleep apnea or cardiovascular disease

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