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The NF-B pathway is activated by pro-inflammatory factors such as TNF- and IL-6 [24], enhancing transcriptional activity through receptor-mediated downstream signaling cascades, inducing the expression of E3 ubiquitin ligase genes atrogin-1 and MuRF1, thereby driving muscle protein degradation via the UPS [25]
398 Zhou, H
Abdomen: Uncover the abdomen to see the whole area
Heymsfields key contributions is his involvement in the discovery and development of GLP-1 receptor agonists, a class of drugs that have become a major breakthrough in obesity treatment
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