Exenatide retains historical significance as the first GLP-1 agonist and may serve as a lower-cost option in resource-limited settings, but liraglutide is the preferred agent for new prescriptions among these two options
These medications fundamentally shift how the body manages energy and hunger, offering powerful tools for those struggling with chronic weight issues or type 2 diabetes
The earliest realistic timeline for UK availability is 2028 or later, following anticipated phase 3 data in 20252026, a potential MHRA submission in 20262027, and subsequent NICE appraisal
Since GLP-1 drugs were designed to fix insulin signaling in the body, they appear to fix the brains metabolism too, which helps it clear out toxic waste like amyloid
The programs often focus on lifestyle change include coaching, nutrition/diet and exercise support