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Next-Generation Modalities Cutting-edge platforms such as: RNA and gene-silencing technologies DNA-encoded therapeutics are opening entirely new possibilities for precision metabolic interventions
Every patient receives baseline metabolic screening, weekly check-ins during the first month, and biweekly follow-ups thereafter to catch emerging symptoms before they become dangerous
The percentage of participants who met the criteria for resolution of MASH without worsening of fibrosis was 10% in the placebo group, 44% in the 5 mg tirzepatide group (difference versus placebo 34%
What you should know
Since 2015, large-scale cardiovascular outcome trials (CVOTs) have demonstrated that sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) significantly reduce the risk of major adverse cardiovascular events, cardiovascular mortality, and heart failure hospitalization in patients with T2DM and established cardiovascular disease or high-risk profiles
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