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Reason for caution: Slowing stomach emptying in someone who already has impaired motility can lead to severe bloating, vomiting, abdominal pain, and inability to maintain nutrition
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The FDA sent over 50 warning letters in September 2025 to companies doing it anyway
Tolerability and effectiveness of glucagon-like peptide-1 receptor agonists in patients with inflammatory bowel disease
But ipamorelin and CJC-1295 combinations often produce superior long-term muscle gains with fewer side effects, making the initial slower progress worthwhile
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