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doi:10.3390/biomedicines11041027
When erastin and/or the iron compound ferlixit were used to induce ferroptosis in HEY, COV318, PEO4 and A2780CP ovarian cancer cell lines, it was found that erastin treatment was accompanied by NCOA4-mediated ferritin phagocytosis and mitochondrial dysfunction in HEY cells with high intracellular unstable iron pools (58)
In addition to preventing protein glycation, PLP is an effective inhibitor of lipid (fat) glycation (Higuchi 2006)
Table 6: Results at Week 52 in a Trial Comparing TRESIBA to Insulin Glargine U-100 (Study A) and Week 26 in a Trial Comparing TRESIBA to Insulin Detemir (Study B) in Adult Patients with Type 1 Diabetes Mellitus Receiving Insulin Aspart at Mealtimes 1At Week 52 2At Week 26 *The change from baseline to end of treatment visit in HbA1c was analyzed using ANOVA with treatment, region, sex, and anti-diabetic treatment at screening as fixed effects, and age and baseline HbA1c as covariates
Subcutaneous (SQ) injections
