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Also, hormonal changes that occur at certain stages of life, such as menopause in women, can cause collagen breakdown, dryness, sagging skin and wrinkles, but also greater bone porosity and joint sensitivity
A prolonged deficiency leads, in the worst case, to lethal anemia, irreparable nerve damage, severe paralysis, chronic pain, severe mental and psychological symptoms and a complete lack of energy
The important task of gathering all these materials may be a challenge for some researchers
Increasing evidence from clinical and animal studies suggest that hair greying is an independent predictor of serious dermatological pathologies and other conditions [200], such as vitiligo [133], cardiovascular diseases[41], oculocutaneous albinism [197], and osteoporosis[167]
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