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Transcription of NLRP3 and inflammatory factors is upregulated through the Toll-like receptor (TLR)-mediated NF-B pathway in response to various cellular stresses, including ROS, mitochondrial damage, and lysosomal destabilization, promoting inflammasome oligomerization and recruitment of other components (Coll et al., 2022)
They are listed here as a reference for researchers investigating Dihexa
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